The Hoops, who are bottom of the Premier League table, have the chance to close the gap on 17th-placed Villa to a point with victory at Villa Park.
Redknapp can call upon vastly experienced stars like Júlio César, Chris Samba and Park Ji-Sung, who have competed in countless high pressure matches throughout their decorated careers.
In contrast, Lambert’s side is largely composed of young talent who are getting their first taste of a relegation battle, and Redknapp reckons the Hoops can use this to their advantage.
“Hopefully the experience we’ve got will help,” said Redknapp.
“We’ve got some big-game players here who have been there and done it. Hopefully that will be in our favour.
“We’ve got to start well. We can’t give them an early start. We can’t concede an early goal and give them a lift.
“It was a good result for them at Reading last week. They’re a decent team with a good, young manager.”
And Redknapp hopes sides such as Newcastle, Norwich and Sunderland could get sucked into the relegation mire as the Hoops look to beat the drop
“You just wish there were a few teams a little bit above us who were still in it,” he added.
“At the moment, ourselves Reading, Wigan, Villa and possibly Southampton, are involved.
“Even teams on 30 points won’t feel 100 per cent safe and need a win or two to be assured. Teams go nine games without a win in this division.
“We’ve seen that happen quite a few times. We just need to win and keep going, it would really make a difference.”
“It’s a massive games for us, without a doubt. It’s a real big one.”
MORE: Delph reverses the trend