The 49-year-old, who is expected to sign a three-year deal with the Potters, has been out of work since being sacked by Queens Park Rangers last November.
Hughes’ reputation came under fire after failing to win a Premier League game in 12 attempts despite a busy summer of transfer activity at the west London club.
But Stoke chairman Peter Coates was undeterred by Hughes’ reign at QPR, instead speaking of his admiration for the former Manchester United striker’s track record, whose appointment will be confirmed at a news conference at 1100 BST.
“I look at results,” Coates told the Stoke Sentinel. “He’s also a thoughtful, intelligent man with an intense desire to win.
“We had lots of inquiries about the job, including some very interesting names, but we decided Mark Hughes was a fit for us.
“His record speaks for itself. He has done excellently by anyone’s standards, but we also understand that whoever we choose, some people will disagree and I don’t have a problem with that.”
Stoke confirmed they will hold a news conference to unveil Hughes as their new boss on Thursday morning.