Manuel Pellegrini’s men head to their local rivals’ home ground looking to keep their place at the top of the Premier League table.
The Citizens are currently two points ahead of Louis van Gaal’s side ahead of the game and warmed up for Sunday’s clash with a 2-1 Champions League win over Sevilla in midweek.
United, meanwhile, were held to a 1-1 draw by CSKA Moscow on Wednesday night and beat Everton 3-0 in their most recent top-flight outing.
And former Arsenal man Merson is backing Van Gaal’s men to claim victory when they host their bitter rivals on Sunday afternoon.
Merson told Sky Sports: “I don’t see United losing this one. City are just too open for my liking and tactically naive at times. They just go all-out attack, which is fine against lesser teams, but United will be solid and could then pick them off.
“United had the biggest result last weekend winning at Everton in the manner they did after their thumping at Arsenal.
“If United win this they are big players in the Premier League title race. Kevin de Bruyne is different gravy and United will have to keep him quiet, he has been outstanding.
“Other than him I don’t see how City hurt can United without Sergio Aguero and David Silva and I think United will just win the game, although a draw wouldn’t surprise me.”
United have won six of their opening nine top-flight games this season, while City are top having secured the three points on seven occasions.
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