The 19-year-old full-back suffered a ruptured anterior cruciate ligament in England Under-21 side’s 3-0 victory over Kazakhstan on Tuesday night.
Gomez’s Liverpool team-mate Danny Ings succumbed to a serious knee injury in his first training session under new manager Jurgen Klopp after having made his England debut in a 3-0 win against Lithuania on Monday.
The former Charlton Athletic defender took to Instagram to post a message after it emerged Gomez could miss up to six months of the new Premier League season.
Gomez wrote on the photo-sharing app: “Me & @ingstagram10 will be back at it soon. Thanks everyone”
Ings scored Liverpool’s goal in a 1-1 draw with Everton in the Merseyside derby in Brendan Rodgers’s final game in charge of the Reds.
Klopp will take control of the 18-time English champions for the first time against Tottenham Hotspur at White Hart Lane on Saturday afternoon.
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