Gomez, who moved to Liverpool from Charlton Athletic in the summer transfer window, ruptured his cruciate ligament injury representing England’s Under-21 side.
The Reds suffered a further blow after Ings was ruled out for the rest of the season after the summer signing picked up a serious knee injury in his first training under new manager Klopp.
The 48-year-old German is also set to be without his predecessor’s big-money summer signings Christian Benteke and Roberto Firmino for Saturday’s game against Tottenham Hotspur at White Hart Lane.
Former Liverpool and Spurs goalkeeper Clemence believes injuries to Gomez and Ings are a massive blow to the new Reds boss.
— Ray Clemence (@RayClem1) October 16, 2015
Liverpool are 10th in the Premier League table but just six points behind leaders Manchester City.
The Reds sacked Brendan Rodgers after a 1-1 draw with Everton before the international break.
MORE: Man United latest news
MORE: Arsenal latest news
MORE: Chelsea latest news
MORE: Liverpool latest news