The Gunners host Hull City at the Emirates Stadium in a repeat of the 2014 final at Wembley.
Arsenal came from 2-0 behind to win 3-2 and secure their first piece of silverware in nine years thanks to Aaron Ramsey’s winner in extra-time.
Tottenham are in action against Crystal Palace just weeks after Spurs were impressive 3-1 winners against Alan Pardew’s side in the Premier League.
Harry Kane, Dele Alli and Nacer Chadli all scored at Selhurst Park to secure three points but could Mauricio Pochettino rest some of his biggest names ahead of the visit of Fiorentina on Thursday?
Undoubtedly the glamour tie of the fifth round is at Stamford Bridge on Sunday evening when Chelsea host Manchester City. The Citizens won 3-0 against the defending Premier League champions at The Etihad in the summer.
For those who fancy playing some online bingo or poker instead of having a punt on the FA Cup action, plenty of casino games at Betway.
Later this week, Arsenal will be in action against Barcelona in the first leg of their Champions League last-16 tie at the Emirates Stadium. Liverpool, Manchester United and Tottenham Hotspur will also play the second leg of their Europa League last-32 clashes on Thursday.
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