The French defender was substituted at half-time during last weekend’s 2-1 win over Leicester City after suffering a dead leg but Wenger confirmed that he is available for this weekend’s fifth-round tie.
The Arsenal manager also revealed that fellow defender Gabriel Paulista is around a week away from being fit again after suffering a slight hamstring injury.
Speaking at a news conference at Arsenal’s London Colney training ground on Friday morning, Wenger said: “Koscielny will be available – he has a test today.
“Gabriel is still out and will need one more week.”
The Arsenal boss also confirmed that midfielder Jack Wilshere is around three to four weeks away from a return to action for the north London side.
Wilshere is yet to feature for Arsenal this season after undergoing surgery on his ankle before the start of the campaign.
He added: “Wilshere will be back in three or four weeks.”
MORE: Latest Man Utd news
MORE: Latest Arsenal news
MORE: The latest football news