The Red Devils have a point to prove after a demoralising 2-1 loss to Premier League strugglers Sunderland at the Stadium of Light on Saturday afternoon.
United dropped down to the Europa League after Louis van Gaal’s side finished in third place in their Champions League group.
The 20-time English champions will face Midtjylland for the first time in their history at the Herning Arena in Denmark.
And Blind posted a photo with Jesse Lingard and Chris Smalling during their final training session on Wednesday evening ahead of the first leg.
Blind wrote on his Instagram page: “Getting Ready 👊🏻 #MUFC”
United failed to win away in the 2015/16 Champions League group stage (D1 L2). They are also on a three-game losing streak in the Europa League.
Midtjylland are one of five sides in the round of 32 who qualified for Europe this season as domestic champions along with Basel 1893 (Switzerland), Galatasaray AŞ (Turkey), Molde (Norway) and Olympiacos (Greece), though Molde have since lost their title to Rosenborg.
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