The Gunners head into the game looking to return to winning ways in the Premier League after their shock 2-1 loss to Watford at The Emirates on Tuesday night.
Chelsea are also looking to get back to winning ways after their 1-1 draw with Liverpool in the top flight on Tuesday night.
Chelsea could move 12 points clear of Tottenham with victory over the Gunners at Stamford Bridge on Saturday before Spurs host Middlesbrough later in the day.
However, Pochettino has insisted that he is not worried about the result at Stamford Bridge before his side are in action.
Asked by a reporter at his news conference on Friday if he wants Arsenal to beat Chelsea, Pochettino replied: “No, I don’t care (smiling).”
Chelsea are the heavy favourites to win the Premier League this season and are nine points clear at the top of the table.
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