The Russian world No.5 was forced to retired following the conclusion of the first set against Francesca Schiavone in Paris and has failed to recover in time for next week’s Championships.
The 28-year-old had originally complained of the calf problem following her quarter-final win over compatriot Nadia Petrova.
Dementieva reached the semi-finals of Wimbledon in 2008 and 2009.
Earlier this year, Dementieva retired from her Dubai Tennis Championships second-round match against Daniela HantuchovÃƒÂ¡ with a shoulder injury.
MORE: The latest football news
MORE: The latest tennis news
BIOGRAPHY: Daniel Sturridge
BIOGRAPHY: Kepa Arrizabalaga