The 20-year-old Dane was able to see off her opponent in straight sets 6-3, 6-4, without having hit top gear in Melbourne.
Wozniacki will now meet Francesca Schiavone in the last eight after the Italian beat Svetlana Kuznetsova of Russia 6-4, 1-6, 16-14, in an epic encounter which lasted almost five hours.
Meanwhile, 2008 winner Maria Sharapova crashed out Down Under after losing to Germany’s Andrea Petkovic in straight sets.
Sharapova, the 14th seed, hit 30 unforced errors on her way to defeat as 33rd seed Petkovic sealed her last eight place in 79 minutes. In sealing her progression, Petkovic became the first German to reach the quarter-finals of the Australian Open since Steffi Graf in 1999.
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BIOGRAPHY: Ethan Hazard
BIOGRAPHY: Daniel Sturridge