Spurs have managed to pick up just two points from their opening three Premier League games, with Norwich City and West Bromwich netting late equalisers to deny the Londoners victory in their last two games.
Defoe, who signed a new three-year deal at White Hart Lane last week following intense speculation over his future, is sure Villas-Boas will be a hit at Spurs and has called for patience from the Spurs hierarchy.
“It takes a while to bed in when new players sign,” Defoe told a news conference on Tuesday.
“It feels like a new start for everyone. Straight away there’s going to be pressure but it’s going to take time.
“It’s important to give the manager a chance because it’s early days. We’ve got a strong squad and I’m sure we’re going to be fine.
“A new manager has come in with different ideas and different formations, it’s a different way of playing. A lot of the players haven’t played this way before so it’s going to take time.”
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