The Red Rose take on Fiji at Twickenham on Saturday, before Lancaster’s men pit their wits against the southern-hemisphere trio on successive weekends.
Lancaster led England to four wins in the Six Nations earlier this year, only losing to eventual Grand Slam winners Wales, and the head coach now wants to see his squad’s hard work pay dividends.
“This challenge against the top three in the world is the strongest one we have faced,” Lancaster said.
“We are confident. We have prepared well. I’ve said to the players it’s production time now.
“We’ve got some continuity, we’ve got some consistency in terms of selection and the coaching team and we’ve spent some time together.
“The foundations are strong. Now we want to deliver.”
Exeter Chiefs flanker Tom Johnson insisted England will take the game to their opponents in the autumn internationals after coming so close to beating South Africa this summer.
“I know the level we played at in South Africa and we are going to have to step up from that to get the results we want from this series,” said Johnson.
“Unless you go after them you can’t stop them. We are going to try and be proactive and take the game to them and not sit back and take it.
“We have got to try and lay down that foundation and make Twickenham the fortress it once was.”
MORE: The latest football news
MORE: The latest tennis news
BIOGRAPHY: Daniel Sturridge
BIOGRAPHY: Kepa Arrizabalaga