The British No3 went down 7-5 7-5 to her 18-year-old opponent, despite being 5-2 up in the second set.
Meanwhile, 21-year-old Brit Johanna Konta reached the second round of qualifying with a battling 6-3 6-7 6-4 win over Anastasia Sevastova of Latvia. Konta will take on China’s Zhou Yimiao in the next round.
British duo Jamie Baker and James Ward won their opening matches in qualifying on Wednesday. Three wins are required to make the singles main draw at Melbourne Park.
The Australian Open gets under way on 14 January.
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BIOGRAPHY: Unai Emery
BIOGRAPHY: Adam Lallana