There are no Premier League representatives in the 11-man side, with eight of the players featured plying their trade for either Barcelona or Real Madrid.
It is the second time this month that players from the English top flight have been ignored in a dream team after no Premier League footballers were included in the FIFPro World XI at the Ballon d’Or gala.
Four-time Ballon d’Or winner Messi lines up alongside rival Ronaldo in the European team, which was compiled after 5.3 million users had their say on Uefa.com.
Thiago Silva, Philipp Lahm and Andrea Pirlo are the only three players included who do not ply their trade at a Spanish club.
Ronaldo makes a record seventh appearance in the line-up along with Real Madrid team-mate Casillas, who makes the cut for the sixth year running.
Tottenham’s Gareth Bale was the sole Premier League representative in the 2011 edition, while Chelsea’s left-back Ashley Cole flew the English flag in 2010.
Iker Casillas (Real Madrid & Spain), Sergio Ramos (Real Madrid & Spain), Gerard Piqué (Barcelona & Spain), Thiago Silva (AC Milan/Paris Saint-Germain), Philipp Lahm (Bayern München & Germany), Andrés Iniesta (Barcelona & Spain), Xavi Hernández (Barcelona & Spain), Andrea Pirlo (Juventus & Italy), Mesut Özil (Real Madrid & Germany), Lionel Messi (Barcelona), Cristiano Ronaldo (Real Madrid & Portugal).
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