Brendan Rodgers’ Reds surged into a second-minute lead after defender Glen Johnson’s low cross was deflected past Tottenham goalkeeper Hugo Lloris by Spurs captain Younes Kaboul.
And things soon got worse for Sherwood’s visitors when a sloppy Michael Dawson pass allowed Luis Suarez to break free and make it 2-0.
It was a shame our mistakes got punished the way we did
Philippe Coutinho made it three shortly after the break, before Jordan Henderson’s strike added further gloss to the scoreline and hoisted Liverpool up to the top of the Premier League.
The defeat left Spurs sixth in the table and eight points behind fourth-placed Arsenal with six games left to play.
And Sherwood felt his side’s slow start on Merseyside ended up costing them any chance of a result.
“The game was pretty much finished after two mistakes early on,” said Sherwood. “They took a lot of belief from that and went from strength to strength.
“We were beaten by better side. It was a shame our mistakes got punished the way we did.”
Spurs have only taken one point against teams in the top four this season – a record Sherwood accepts is not acceptable.
“It is not good,” he said. “Perhaps is is a belief thing – a lot of these teams are better than us.
“We don’t have opportunity to put it right but we owe it to ourselves to get maximum points from our last six games.”
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