The Spanish goalkeeper helped the Red Devils record their second league win of the season as they sealed a 2-1 victory over West Ham at Old Trafford.
Goals from Wayne Rooney and Robin van Persie helped Louis van Gaal’s side bounce back from last weekend’s 5-3 loss to Leicester City.
And De Gea posted the picture above on Instagram after reaching the milestone with the club.
He wrote: “Very proud of having played 100 @premierleague matches with a club such as @ManchesterUnited Thanks for your support!! #MUFC”
Spain international, who has two senior caps to his name, De Gea joined United from Atletico Madrid in 2011.
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