The Reds have been forced to adapt to life without Luis Suarez after the Uruguay striker sealed a big-month transfer to Barcelona earlier in the summer.
Brendan Rodgers’ men have notched up two wins from their opening three games, with the Merseyside outfit securing an impressive 3-0 victory at Tottenham following their defeat by City at Etihad Stadium
Liverpool finished second in the table last season as City notched up their second top-flight title in three seasons.
But midfielder Nasri feels that the Reds will struggle to mount a title challenge this season.
“Liverpool will find it tougher because they have lost Luis Suarez and they will be playing Champions League football so it will be different for them,” Nasri told ESPN.
“Last season they only had the Premier League to go for in the final months and it gave them a real advantage because their players were going into games fresher at a vital stage of the campaign.”
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