The midfielder suffered the injury during the second half of the 2-1 defeat by Manchester United on Saturday and sat out Wednesday’s win over Borussia Dortmund.
An Arsenal statement read: “Jack Wilshere has had successful surgery on his left ankle and will be out for approximately three months.
“An assessment with a specialist confirmed the need for an operation and the 22-year-old had successful surgery to his ankle in London on Thursday afternoon.
“Jack will now commence his injury rehabilitation programme with the Arsenal medical team.
“Everyone at the club wishes Jack a speedy recovery and look forward to seeing him back on the pitch as soon as possible.”
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