The north London side were fortunate to edge to a 2-1 victory over Asteras Tripolis in the Europa League on Thursday night after a mixed performance.
Tottenham can record their third straight win in all competitions with victory over Stoke at White Hart Lane, and Vertonghen wants Spurs to avoid another post-Europa League slump.
“It was strange because we didn’t win second balls,” Vertonghen is quoted as saying by London24.
“That team can play and the most important thing was they felt they could do something against an English team.
“I have been in that position with Ajax playing bigger teams and if you can get some hope you start playing differently and that’s what we gave them ourselves.
“It is a long way off building a winning mentality like Ajax. It is not a case of pick the line-up and you win every game since then. You can have ups and downs.
“Of course, we won, but it was not that positive, so we have to analyse this game and see where it went wrong. Then we have to continue and avoid making those mistakes in the next game.
“That’s what we have to do against Stoke, because if we make these mistakes against Stoke probably we will lose this game.”
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