The Chilean has been in fine form for the north London club since his £35m transfer to Emirates Stadium from Barcelona last summer but has struggled to replicate some of his early-season performances in recent weeks.
Sanchez, 26, has scored 19 goals in 40 games for the Gunners this season and is in line to feature when Arsenal travel to Newcastle United in the Premier League on Saturday afternoon.
But Wenger has conceded that the attacker has suffered from a dip in energy levels in recent weeks.
“He’s a bit fatigued and in a position where he has scored less,” Wenger told an Arsenal news conference last week.
“He wants to force his game and then is more involved in physical battles. Maybe goalscoring is on his mind, so he wants to do too much and he wants to force his game.
“I’m tempted to give him a break at some stage. I have been for a long time.
“It’s not that he won’t let me, I will decide that. It’s just that every game now is so important, you always have a hesitation to do it.”
Arsenal have won their last six games against Newcastle, scoring 18 goals and conceding five.
Wenger’s men are in fine form, having won 13 of 15 games since New Year’s Day, including eight wins from nine league matches.
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