Liverpool host United looking to gain revenge on their bitter local rivals following their 3-1 loss at Old Trafford back in September.
Arsenal, meanwhile, travel to Stoke City looking for a result to move them back to the top of the Premier League table after their 3-3 draw with Liverpool in midweek.
The Gunners, who finished third last term, are looking to win their first Premier League title since the 2003-04 season.
Former Manchester United and Liverpool striker Owen used his personal Twitter account to give his take on the games as the build-up continued.
Owen tweeted on Sunday morning:
In London for today's double header on the PL world feed. Stoke and Arsenal haven't gotten on recently, Liverpool and United never have!
— michael owen (@themichaelowen) January 17, 2016
United have only won three of their last 10 Premier League games following a stuttering run of recent form for Louis van Gaal’s men. Liverpool, meanwhile, have only won four of their last 10 top-flight games.
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