United have their work cut out in trying to book their place in the last eight of Europe’s second tier club competition after they were thoroughly outplayed in last week’s 2-0 loss at Anfield.
Louis van Gaal’s men have come in for plenty of criticism for their below-par performance on Merseyside last week.
However, United midfielder Herrera is sure that he and his team-mates will be able to turn the tie around in front of their home fans at Old Trafford.
Speaking at a news conference on Wednesday afternoon, Herrera said: “They have not been too comfy playing here in front of our fans. We have done it before and we have the capacity to do it again.
“We feel stronger when we play at home. We will have more fans at home. The capacity of this stadium is bigger than Anfield.
“We have the best fans in England and they will be very important.
“We should have played much better in the first game but we have another chance. We learned a lot from the game at Anfield and the second leg will be totally different. The pitch is bigger, the grass is better here.”
United head into the game after battling back from a goal down to earn a 1-1 draw against West Ham in the FA Cup quarter-finals at Old Trafford on Sunday afternoon.
MORE: Man United latest news
MORE: Arsenal latest news
MORE: Chelsea latest news
MORE: Liverpool latest news