Jurgen Klopp’s side will host the Red Devils in the first leg of their Europa League last-16 tie as both Premier League clubs look to reach the Champions League next season.
Liverpool have won their last three Premier League games after scoring 11 goals in victories over Aston Villa, Manchester City and Crystal Palace.
United, on the other hand, lost 1-0 to West Bromwich Albion on Sunday which ended their four-game winning run in all competitions.
Former Arsenal defender Dixon didn’t feel comfortable picking a winner given the unpredictable nature of the north-west derby.
“Obviously the winner of this gets Champions League qualification. That’s a big thing for both of them. That’s the carrot at the end,” Dixon told ITV Sport.
“You can never call that game. Every Liverpool v Man Utd game, whoever is in form, that game you know it will be fireworks.”
Liverpool are unbeaten in eight European games this season (W3 D5), and have not lost in six home matches (W3 D3).
Enhanced odds: Get 10/1 on Man Utd to beat Liverpool
They have not lost in eight UEFA Europa League home fixtures (W5 D3) since a 3-2 defeat by Udinese Calcio in the 2012/13 group stage.
United’s record in six Europa League matches to date is W2 D0 L4 (W1 D0 L2 at home – W1 D0 L2 away).
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