The same report states that Arsenal are also interested in Hoffenheim star Fabian Schar as a potential alternative to Mustafi should the Gunners miss out on the Valencia man.
Wenger has already signed one Switzerland international this summer after the Gunners completed a £33m deal for Granit Xhaka from Borussia Monchengladbach ahead of European championship.
Arsenal are currently facing something of a defensive crisis after injuries to Germany international Per Mertesacker and Brazilian Gabriel Paulista.
Laurent Koscielny is also regaining his fitness after an extended summer break after helping France reach the Euro 2016 final in July.
Wenger started inexperienced centre-halves Calum Chambers and Rob Holding in Arsenal’s Premier League opener on Sunday afternoon as the Gunners lost 4-3 to bitter rivals Liverpool at the Emirates Stadium.
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