Jurgen Klopp’s side have won their last four Premier League games thanks to victories over reigning champions Leicester City, top-four rivals Chelsea, promoted side Hull City and Swansea City.
Liverpool are in fourth place in the Premier League table and two points behind leaders Manchester City ahead of the north-west derby on Merseyside.
United, meanwhile, have notched up one victory in their last four Premier League outings after defeats by Manchester City and Watford before a 1-1 draw with Stoke City last time out.
Jose Mourinho’s side are in sixth place in the Premier League table and three points behind fourth-placed Liverpool.
Former Liverpool and United striker Owen admitted that he is finding it hard to pick a winner for Monday night’s bitter clash at Anfield.
“It’s always special and you want it to be a game that is deciding things at the top of the league,” Owen told United’s website.
“In the last three years, United have been off the pace a little bit, while Liverpool challenged for the league a few seasons ago but haven’t really had a strong challenge since.
“Both have chances of doing something this season and that just adds to the spice of it. United had a few decent results before a bit of a blip against Stoke, whereas Liverpool are looking strong at the moment so it will be an interesting game.”
Liverpool were 3-1 aggregate winners against Manchester United in the Europa League last season following a 2-0 win at Anfield in the first leg thanks to goals from Roberto Firmino and Daniel Sturridge.
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