The Red Devils signed Sanchez in a swap deal from Arsenal in the January transfer window as Henrikh Mkhitaryan completed a move to Manchester United.
Sanchez has struggled to adapt to life at Manchester United despite arriving at Old Trafford having established himself as a top Premier League player.
The South American has only managed to score one goal in 10 appearances in a Red Devils shirt so far.
Sanchez is suffering through an eight-game goal drought but Mourinho has stuck with the South American forward despite his obvious struggles.
The Chile international was subdued during Manchester United’s 2-1 loss to Sevilla in the second leg of their Champions League last-16 clash last week.
Former Arsenal striker Wright believes Sanchez need to be given some time off to rekindle his confidence.
“When is the time going to come when he will say it isn’t quite working with Sanchez and I will take [him] out [of the team]?” Wright told Sky Sports.
“Maybe it will give him that kick again.
“I am not saying drop Sanchez but at some stage Mourinho [needs to] given he isn’t bothered about dropping Pogba.”
Sanchez netted 24 times in 38 games in the Premier League last season to finish behind Harry Kane and Romelu Lukaku.
Manchester United haven’t won the Premier League title since 2013 when Sir Alex Ferguson led the Red Devils to the top-flight crown.
MORE: Man United latest news
MORE: Arsenal latest news
MORE: Chelsea latest news
MORE: Liverpool latest news