The Gunners have been in better form in recent weeks after a difficult spell for Arsene Wenger’s men left them adrift of the top four in the Premier League.
Arsenal followed up their victory over Stoke City last weekend by beating CSKA Moscow 4-1 in the first leg of their Europa League quarter-final tie at The Emirates on Thursday night.
The north London side are aiming to try and win the Europa League this season to try and secure their place in the Champions League for next term, with Wenger’s men currently in sixth place in the table.
Nevertheless, Arsenal will be hoping to beat Southampton and keep some momentum ahead of their trip to Moscow to take on CSKA in the return leg on Thursday night next week.
And former Liverpool FC star Lawrenson is not expecting the Gunners to have any problems against the Saints this weekend.
Writing in his column for BBC Sport, Lawrenson said: “I said on Football Focus last week that Arsenal’s form is a bit like when you are feeling ill and take some antibiotics – you think you are cured but actually you are still not right.
“The Gunners have won two league games on the trot now, but they are still Arsenal and they are still fragile. Even if they win every game between now and the end of the season, they still need an operation.
“They will beat Southampton at home, though.
“Saints were turned over very easily by West Ham last week, which showed how big a job Mark Hughes faces to try to keep them in the Premier League.”
Arsenal finished in fifth place in the Premier League table last season and it looks as though they will miss out on a top-four finish for the second season running.
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