The French midfielder has found himself under the spotlight in recent months after failing to produce consistent form for the Red Devils.
Pogba has been in and out of the first team at Old Trafford and has struggled with injury this season, prompting questions about his long-term future at the club.
However, Mourinho has insisted that he is working hard to try and get the best out of Pogba as the Red Devils look to enjoy a positive end to the season.
Speaking at a news conference at Carrington on Friday, Mourinho said: “I work (to get the best out of him). It’s the only thing I can do. I cannot do anything else. This season and also last season (he had a bad injury).
“I think he is very fine after the injury. It was a difficult injury, it was an injury that other players, other clubs, other medical assessments, they end in surgery.
“His option with the medical opinions was not to go to the surgery table and his recovery was really, really good.
“I think he is more than fine in relation to the recovery from the injury, which is a muscular area sometimes where you have a recurrence. In his case, not at all.”
Pogba re-joined Manchester United from Juventus for a then-world-record transfer fee back in the summer of 2016 following Mourinho’s appointment at Old Trafford.
Manchester United were knocked out of the Champions League by Sevilla last month to leave them playing for the FA Cup and a top-four finish in the Premier League this season.
The Red Devils finished in sixth place last term and won the Europa League and the League Cup in what was Mourinho’s first campaign in charge.
Manchester United travel to Manchester City in the Premier League next weekend.
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