Spurs will welcome the Premier League leaders to the home of English football after a third successive defeat for Pep Guardiola’s side.
Manchester City hosted Liverpool FC in the second leg of their Champions League quarter-final on Tuesday night after a 3-0 loss at Anfield last week.,
The Citizens broke the deadlock in the second minute through Gabriel Jesus before Mohamed Salah and Roberto Firmino scored in the second half to secure a 2-1 win for the visitors.
Manchester City squandered a 2-0 lead in the Manchester derby last weekend after goals from Paul Pogba and Chris Smalling rescued a 3-2 win for Manchester United.
Tottenham haven’t lost a Premier League game at Wembley since a 2-1 loss to defending Premier League champions Chelsea in their second game of the English top flight.
Former Liverpool FC striker Owen is backing Spurs to condemn Manchester City to a fourth consecutive loss in all competitions.
“Manchester City have played two great halves of football against United and Liverpool this week but they were not able to sustain that brilliance over 90 minutes and it has to go down as a disappointing week for the club,” Owen told BetVictor.
“That should not detract, however, from a magnificent season for the team and they will be fitting champions – even if the champagne is currently on ice.
“Spurs have won their last two home league games against City and the visitors would not be human if they did not feel a little sorry for themselves.
“These two sides can only play one way and that is to attack, but I feel the hosts will keep the points in the capital.”
Tottenham finished in second place in the Premier League table last term and above Manchester City in the top-flight standings.
Spurs will take on Manchester United in the FA Cup semi-finals at Wembley later this month.
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