The north London side bounced back from a 1-0 deficit to ease to a comfortable win over the Foxes and extend their winning run to seven games in the Premier League.
Hector Bellerin scored an own goal in the first half to cap a disappointing performance from Arsenal in the opening 45 minutes at Old Trafford.
The Gunners equalised on the stroke of half-time when Ozil scored his third Premier League goal of the season thanks to his instinctive finish.
The former Germany international edged into a 2-1 lead after the 30-year-old teed up Pierre-Emerick Aubameyang to score his fifth league goal.
The January signing polished off a commanding win with the north London side’s third goal after Ozil had played a role in the build up.
And the Arsenal star was delighted to be part of such a stylish performance from Unai Emery’s side to move to within two points of leaders Manchester City and Liverpool FC.
Ozil wrote on his Instagram page: “I think we played some sexy football tonight 😎💪🏼 Proud captain of this team and this club! © #YaGunnersYa ❤ #M1Ö @arsenal”
The former Real Madrid playmaker called time on his international career after Germany’s disappointing group-stage exit at the World Cup in Russia.
And the Arsenal number 10 appeared to benefit from a fortnight’s rest before the return of the Premier League.
Ozil moved to the north London side in a £42.5m deal from La Liga giants Real Madrid in the 2013 summer transfer window in what was then a club record transfer.
The World Cup winner has got his hands on three FA Cup titles during his spell at Arsenal but Ozil hasn’t been able to transform the Gunners into title winners.
Arsenal are level on points with third-placed Chelsea FC in the Premier League table in pursuit of a top-four finish.
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