The Merseyside outfit made a promising start to their European campaign after Liverpool FC were 3-2 winners against Paris Saint-Germain at Anfield back in September.
Liverpool FC looked set to settle for a point at Napoli before Italy international Lorenzo Insigne came off the bench to score a dramatic winner on the stroke of full-time.
The Reds are in second place in the Champions League group and a point adrift of Napoli, who have collected four points from their opening two group stage fixtures.
Jurgen Klopp’s side have the chance to put themselves in a strong position to qualify for the knockout stage with successive games against Red Star Belgrade.
The Serbian outfit lost 6-1 at home to PSG in their last outing after Red Star played out a goalless draw with Napoli.
Liverpool FC will be looking to exact revenge for their losses to the Serbian club in 1973, when Red Star beat Bill Shankly’s men both home and away in the European Cup quarter-final.
Former Liverpool FC striker Owen, who was part of their treble-winning side in 2000-01, is backing Klopp’s men to secure a home win at Anfield on Wednesday night.
“Crevena Zvezda have only won one of their last eight games in European competition -excluding qualifiers – and Liverpool are taken to gain a comprehensive win and put behind the loss in Naples on Matchday two,” Owen told BetVictor.
“The Reds – excluding qualifiers – are unbeaten in their last 16 home games in Europe and have scored 39 times in the process. After what was a functional win at Huddersfield at the weekend, I take the Reds to return to their fluent best against the Serbs.”
Red Star were the first European team to beat Liverpool FC in Uefa competitions at Anfield when the prestigious club were 2-1 winners thanks to a 90th-minute winner.
Liverpool FC haven’t faced another Serbian club in the next 45 seasons before Red Star were pitted against the five-time European champions this season.
The Merseyside outfit scored an average of 3.15 goals per game in the 2017-18 UEFA Champions League but Klopp’s attack have made a stuttering start to the current campaign.
Liverpool FC were 1-0 winners against Huddersfield Town in the Premier League on Saturday evening thanks to Mo Salah’s winner.
MORE: Man United latest news
MORE: Arsenal latest news
MORE: Chelsea latest news
MORE: Liverpool latest news