The Gunners will make the long trip to Manchester fresh from a morale-boosting 4-2 victory over Tottenham Hotspur in the north London derby at the weekend.
Goals from Pierre-Emerick Aubameyang, Alexandre Lacazette and Lucas Torreira helped Arsenal to come from behind to secure a famous win in a six-goal thriller at The Emirates.
Arsenal hoisted themselves above Tottenham and into fourth spot in the Premier League table in the race to secure the final Champions League spot.
The Gunners will be hoping to extend their 12-game unbeaten run when Unai Emery’s men take on an out-of-sorts Manchester United side.
The Red Devils were held to a 2-2 draw with relegation candidates Southampton on Saturday evening to lose further ground on the top four.
Manchester United are in seventh place in the Premier League table and eight point adrift of Arsenal in the final Champions League spot.
Former Liverpool FC striker Owen is backing Arsenal and Manchester United to share the spoils at Old Trafford on Wednesday night.
“Arsenal have not won at Old Trafford in the Premier League since September 2006 and I feel they will have to settle for a point despite going into the game on the back of a 4-2 win over North London rivals Spurs on Sunday,” Owen told BetVictor.
“Arsenal are unbeaten in their last 19 competitive games and continue to improve under Unai Emery. United did well to come from two-down to get a draw at St Mary’s on Saturday, but they are not convincing at either end of the pitch at present.”
Manchester United are unbeaten in 11 games against Arsenal at Old Trafford since September 2006.
The Red Devils did the double against Arsenal last season after a 2-1 win at Old Trafford followed by a 3-1 victory at The Emirates.
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