The Gunners head into the game looking to claim a victory to boost their hopes of finishing in the top four this season.
The north London side are currently fifth in the Premier League table after having beaten Blackpool 3-0 in the FA Cup third round last weekend.
Meanwhile, West Ham United currently find themselves in 10th place in the Premier League table under Manuel Pellegrini.
Arsenal have struggled to find consistent form in the Premier League in recent weeks and have only won two of their last five outings in the top flight.
And Owen seems to think that West Ham United would be the more likely winners on Saturday lunchtime at the London Stadium.
Writing in his column for BetVictor, Owen said: “Arsenal are unbeaten in their last 11 away games against West Ham in all competitions, but if there is to be a winner at the London Stadium I feel it will be the hosts, as I still have my reservations about the Gunners defensive capabilities.
“Yes, the hosts have conceded at least once in their last eight home Premier League games and I would be surprised if the Hammers kept a clean sheet this weekend, but Manuel Pellegrini has never finished on the losing side against Unai Emery in six previous home league games (W4 D2).
“A cracking London derby to look forward to with opportunities at both ends.”
Arsenal are looking to finish in the top four this season after having missed out on Champions League qualification for the last two years running.
It remains to be seen whether Arsenal will bring in any new players this months during the January transfer window.
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