Italian media outlet Gazzetta dello Sport, as quoted by the Daily Mirror, is reporting that the Red Devils are interested in a potential deal to sign the Argentina international this summer.
The same article states that the 20-time English champions are hoping to sign a new striker as Romelu Lukaku appears to head closer to a Manchester United exit this summer.
According to the same story, Dybala is thought to be happy with Maurizio Sarri’s appointment at Juventus after the former Chelsea FC boss moved to Turin at the end of June.
Manchester United have been regularly linked with a move to sign Dybala over the past 12 months but a deal for the Argentinian forward has failed to materialise.
Dybala was facing more competition for a starting spot last season after Manchester United legend Cristiano Ronaldo arrived from Real Madrid in a £100m deal.
The 25-year-old scored five times and made four assists in 30 games in Serie A last season.
Manchester United have signed two new players in the summer transfer window as manager Ole Gunnar Solskjaer looks to stamp his authority on the Red Devils squad.
The Red Devils snapped up Daniel James in an £18m deal from Swansea City before Crystal Palace defender Aaron Wan-Bissaka moved to Manchester United in a £50m deal earlier this month.
MORE: Man United latest news
MORE: Arsenal latest news
MORE: Chelsea latest news
MORE: Liverpool latest news