The Citizens can secure their place in the Champions League knockout stage with victory over Shakhtar Donetsk.
Pep Guardiola’s side are sitting at the top of Group C with a five-point advantage over Shakhtar Donetsk and Dinamo Zagreb.
Manchester City were held to a 1-1 draw with Serie A side Atalanta in their last Champions League outing in Italy earlier this month.
However, the Eastlands outfit were 3-0 winners against Shakhtar Donetsk earlier in the group stage.
Former Manchester United striker Owen is backing Manchester City to ease to a straightforward win against Shakhtar Donetsk.
“Manchester City did well to come from a goal down to beat a young and progressive Chelsea side at the Etihad on Saturday,” Owen told BetVictor.
“I expect the Premier League champions to follow up their 3-0 win in Kharkiv on Matchday one with another fluent success against the Ukrainians.
“A win would guarantee City’s place in top spot in the group, although Shakthar have much to play for themselves given they currently sit second. Another comfortable European night for Pep Guardiola’s side.”
Man City have won three of their four home matches against Ukrainian visitors without conceding in Uefa competitions.
According to Owen, the Citizens can extend that record to four of their last five home fixtures on Tuesday night.
The Eastland outfit’s 6-0 defeat of Shakhtar Donetsk last season was Manchester City’s record win in Uefa competition before Guardiola’s men beat Schalke 04 7-0 in the round of 16 second leg.
Manchester City have lost to English opposition in the Champions League quarter-finals in the last two seasons following defeats by Liverpool FC and Spurs in 2018 and 2019.
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