Jose Mourinho made a winning start to his Spurs reign with a 3-2 victory over West Ham United at the London Stadium at the weekend.
Goals from Son Heung-min, Lucas Moura and Harry Kane sealed a comfortable win for the Lilywhites.
Tottenham can secure their place in the Champions League knockout stage with a win against Olympiakos.
Spurs were 4-0 winners against Red Star Belgrade in their last European outing to cement their position in second place behind group leaders Bayern Munich.
Mourinho will be eager to see Spurs confirm their last-16 spot against the Greek side in north London before a trip to Bayern Munich in their final group-stage fixture.
Former Liverpool FC striker Owen is backing Tottenham to ease to a comfortable win against Olympiakos on Tuesday night.
“Spurs began life under Jose Mourinho with a win against West Ham at the London Stadium on Saturday and a win against Olympiakos will see last season’s beaten finalists safely through to the knock-out stages,” Owen told BetVictor.
“Olympiakos need to win in London to stand any chance of reaching the last 16 but, after picking up just one point from their opening four games, I expect Spurs to have too much for the Greek Super League outfit although it may not be as easy as some would have us believe.”
Spurs had won only one of six games in the Champions League (D1 L4) before the pair of victories against Red Star Belgrade.
After drawing at Olympiakos in their group-stage opener, Spurs were beaten 7-2 in London by Bayern – the first time in the club’s 137-year history that they had conceded seven goals at home in any competition
Tottenham reached the Champions League final last season before a 2-0 loss to Liverpool FC in Madrid.
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