The Gunners head into the game looking to try and bounce back to winning ways after the disappointment of their 2-2 draw with Norwich City at the weekend.
Freddie Ljungberg is in temporary charge at The Emirates as the former midfielder looks to try and reverse the north London club’s ailing fortunes.
Arsenal currently find themselves well off the pace in the race for Champions League qualification and they have only managed to win four of their 13 games in the Premier League this season.
Brighton head into the game looking to bounce back from their defeat by Liverpool FC at Anfield at the weekend, but former Gunners star Nicholas is tipping Arsenal to be able to claim all three points this week.
Writing in his column for Sky Sports, Nicholas said: “What a glorious opportunity for Arsenal, this is the only way you can look at it.
“They had a bit more spike about them at the weekend but Freddie, why are you picking Shkodran Mustafi? When are you going to learn about Calum Chambers?
“I also cannot understand how David Luiz is in the team. He just doesn’t want to run. He is only interested when he gets the ball at his feet. Sokratis Papastathopoulos is a shocker and Mustafi is even worse. Granit Xhaka also cannot run.
“It is such a huge mess. I honestly thought Freddie would not be close to getting the job, but now, I do not know how long he will have in charge. In the end, it may not be their number one target who they end up getting.
“Regarding Freddie’s selection, what have you done there that was different to Unai Emery? I didn’t get it. It might be his first pick, but could also be who he has got fit. Bringing in Joe Willock I understood, but the re-introduction of Xhaka baffled me.
“Mesut Ozil wanted the ball and wanted to get into the pockets of space, he was decent again. There is an enthusiasm about Alexandre Lacazette and Pierre-Emerick Aubameyang.
“Brighton played out from the back and played with confidence and insurance, but this is about Arsenal getting back on the winning trail and trying to threaten the top six, and potentially the top four. They need to ramp up the action.
“The manager has gone and they need results and a winning formula. It will be another tense night though at the Emirates.”
Next up for Arsenal after Thursday night’s game is their trip to West Ham United on Monday night next week.
They will then travel to Standard Liege in their final Europa League group stage game before a crunch Premier League clash at home to defending champions Manchester City.
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