Ranked No10, the Frenchman was the top seed at the Dutch tournament after the last-minute withdrawal of Roger Federer following knee surgery last week.
Gasquet, the defending champion in Montpellier, picked up a groin injury ahead of Sunday’s final, but then also became sick when travelling to Rotterdam.
“I felt pain in the final in the groin, and I am still feeling bad with it, and I feel sick, too,” he said. “So it’s impossible for me to play. Of course, I am very sad: It’s a big tournament for me to play, so very disappointed.
“The day before the [Montpellier] final I was not supposed to play but it was the final so I forced a lot to play, but since that, I have the same injury—but now I am feeling sick too.”
Gasquet had only returned to the tour in Montpellier after back injury forced him to miss the Australian Open. The back, he said, was no longer a problem, but he remains uncertain how long this latest setback will keep him away.
“[Four matches in Montpellier] was a lot for me. I was not supposed to win the tournament because I had not practised so much, and I forced a lot, and I was not ready to play so many matches. Which is why I am not in good shape now. I will try to recover and play as soon as possible.
“Now I need to rest. I don’t want to play if I am not 100 percent here… I need to do exams, to rest, and maybe be able to play in 10 days’ time in Marseille, but I am not sure.”
Gasquet’s place in the draw is taken by lucky loser, world No83 Evgeny Donskoy, who plays Jeremy Chardy tomorrow afternoon.